The winner here will be in good position for a wild card halfway through the schedule. Both teams are on the upswing, with the Vikings taking three in a row and the Rams three of four.
The Rams have visited Minnesota just twice in 23 seasons. Their coach, Jeff Fisher, is 1-6 against the Vikings. For St. Louis to prosper, it will need to keep firing up that league-leading pass rush, but also slow down Todd Gurley.
Gurley is the first rookie in NFL history with four straight games of 125-plus yards rushing. He leads the league with 115 yards per game rushing, and Minnesota star Adrian Peterson is next at 90.4.
St. Louis' defense is ranked sixth in the NFL, utilizing a deep rotation to keep the pressure on opponents and keeping production high without two top starters.
The Rams dominated the last two games, allowing just four field goals.
"We're just raising the bar every week," said tackle Michael Brockers, who had a sack and combined with middle linebacker James Laurinaitis for a safety last week in a 27-6 victory over San Francisco. "We're not being complacent with stats or what everybody is saying about you."