Going on the road on a short week against a division rival is usually a challenge for most teams.
For the defending champion Denver Broncos, it is extra difficult this week.
Coming off their first loss of the season, the Broncos will be without coach Gary Kubiak when they visit the reeling San Diego Chargers on Thursday night.
Kubiak is taking a week off after experiencing a "complex migraine condition" Sunday night shortly after Denver's 23-16 loss to the Atlanta Falcons.
Kubiak was sent home from the hospital Monday and issued a statement saying he was feeling much better, thanking his team's medical staff and expressing his confidence in Joe DeCamillis. DeCamillis, the special teams coordinator, is serving as interim head coach.
Trevor Siemian is expected to return as quarterback for Denver after rookie Paxton Lynch struggled against the Falcons.
The Broncos (4-1) have won 15 consecutive division road games, the longest such streak in NFL history.
The Chargers (1-4) are coming off a 34-31 loss at Oakland, where rookie Drew Kaser botched the hold for a potential game-tying field goal late in the game. It was the 10th straight AFC West loss for San Diego going back to 2014.