San Francisco 49ers wide receiver Deebo Samuel (19) runs past Los Angeles Rams safety Jordan Fuller to score during the second half of an NFL football game in Santa Clara, Calif., Monday, Nov. 15, 2021. (AP Photo/Tony Avelar)

Jacksonville Jaguars quarterback Trevor Lawrence (16) fumbles the ball as he's hit by Indianapolis Colts middle linebacker Bobby Okereke (58) and defensive end Dayo Odeyingbo (54) in the second half of an NFL football game in Indianapolis, Sunday, Nov. 14, 2021. (AP Photo/Darron Cummings)

San Francisco 49ers defensive end Nick Bosa (97) reacts after sacking Los Angeles Rams quarterback Matthew Stafford during the second half of an NFL football game in Santa Clara, Calif., Monday, Nov. 15, 2021. (AP Photo/Jed Jacobsohn)

Indianapolis Colts quarterback Carson Wentz (2) is hit by Jacksonville Jaguars defensive end Adam Gotsis (96) as he throws in the second half of an NFL football game in Indianapolis, Sunday, Nov. 14, 2021. (AP Photo/AJ Mast)