Jacksonville Jaguars quarterback Trevor Lawrence (16) is hit by Indianapolis Colts defensive tackle DeForest Buckner (99) in the second half of an NFL football game in Indianapolis, Sunday, Nov. 14, 2021. (AP Photo/AJ Mast)

San Francisco 49ers quarterback Jimmy Garoppolo (10) passes against the Los Angeles Rams during the first half of an NFL football game in Santa Clara, Calif., Monday, Nov. 15, 2021. (AP Photo/Jed Jacobsohn)

Los Angeles Rams wide receiver Cooper Kupp, right, is tackled in front of San Francisco 49ers cornerback Emmanuel Moseley during the second half of an NFL football game in Santa Clara, Calif., Monday, Nov. 15, 2021. (AP Photo/Tony Avelar)

San Francisco 49ers defensive end Nick Bosa (97) reacts after sacking Los Angeles Rams quarterback Matthew Stafford during the second half of an NFL football game in Santa Clara, Calif., Monday, Nov. 15, 2021. (AP Photo/Jed Jacobsohn)

Jacksonville Jaguars head coach Urban Meyer talks with line judge Tim Podraza (47) in the second half of an NFL football game against the Indianapolis Colts in Indianapolis, Sunday, Nov. 14, 2021. (AP Photo/AJ Mast)

San Francisco 49ers running back Elijah Mitchell (25) runs as offensive tackle Trent Williams (71) blocks Los Angeles Rams inside linebacker Troy Reeder (51) during the second half of an NFL football game in Santa Clara, Calif., Monday, Nov. 15, 2021. (AP Photo/Jed Jacobsohn)

Jacksonville Jaguars quarterback Trevor Lawrence (16) fumbles the ball as he's hit by Indianapolis Colts middle linebacker Bobby Okereke (58) and defensive end Dayo Odeyingbo (54) in the second half of an NFL football game in Indianapolis, Sunday, Nov. 14, 2021. (AP Photo/Darron Cummings)

Indianapolis Colts quarterback Carson Wentz (2) is hit by Jacksonville Jaguars defensive end Adam Gotsis (96) as he throws in the second half of an NFL football game in Indianapolis, Sunday, Nov. 14, 2021. (AP Photo/AJ Mast)