Tennessee Titans defenders Tennessee Titans defenders Jeffery Simmons (98) and Jurrell Casey (99) celebrate after stopping the Los Angeles Chargers on their final drive of the game in the fourth quarter of an NFL football game Sunday, Oct. 20, 2019, in Nashville, Tenn. The Titans won 23-20. (AP Photo/James Kenney)
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NASHVILLE, Tenn. (AP) — Titans linebacker Jayon Brown remembers playing against Christian McCaffrey in college.

Now the former UCLA linebacker gets his first chance to tackle the former Stanford running back in the NFL. Brown said it will be a fun challenge Sunday when the Titans (4-4) visit Carolina (4-3).

"He's the man. He's the man," Brown said of McCaffrey. "That's all I have to say. He's the man. He's cold."

Brown and the Titans are pretty confident they can contain the man with the NFL's No. 4 scoring defense. They're also rank 12th in the league giving up 96.5 yards rushing a game and ninth in yards allowed (335.6).

McCaffrey, who finished second to Titans running back Derrick Henry in the 2015 Heisman Trophy voting, is averaging 154 yards from scrimmage this season. He ranks second with 105 yards rushing and third among running backs averaging 49 yards receiving a game. McCaffrey has 1,078 yards from scrimmage so far, ninth-most in NFL history through the first seven games.

He had 155 yards from scrimmage last week in a 51-13 loss to San Francisco. He's been held below 93 yards rushing only twice this season — both by Tampa Bay.

Titans safety Kevin Byard said McCaffrey is one of the NFL's more elite players and able to attack from anywhere.

"We're definitely going to have to be great tacklers with him, understanding we have to get all 11 to the ball making sure we're wrapping up, swarming this guy because this guy can take it to the house anytime he touches the ball," Byard said.

Looking at McCaffrey on tape has been both agonizing and fun for Titans coach Mike Vrabel, a former linebacker. Vrabel said coaches know McCaffrey will be productive whether he's running or catching passes.

"He'll be patient, and then he's got a burst to hit the hole," Vrabel said. "If you over pursue, he cuts back. If you come in there light on the sidelines, he's going to stiff arm you. He's got a lot of tools, and he uses them very effectively."

McCaffrey is poised to join elite company in NFL history if he gains at least 150 scrimmage yards against the Titans. That would make him only the third player to have at least 150 scrimmage yards in six of his team's first eight games in a season in NFL history, joining Pro Football Hall of Famer Jim Brown (1963 for Cleveland) and Matt Forte (2011 with Chicago).

The Panthers' versatile running back also is 139 yards receiving shy of becoming the first player in NFL history with at least 2,000 yards rushing and 2,000 yards receiving in his first 40 games. McCaffrey already has 2,268 yards rushing to start his career.

Panthers coach Ron Rivera says McCaffrey simply picked up where he left off last season, and Carolina's biggest challenge is not overworking him while not wanting to take the ball out of his hands.

"That's the thing you have to be smart about," Rivera said. "Again, you don't want to over-expose him, but at the same time, you don't want to underuse him. If we can put the ball in his hands at the right time, we can most certainly get a lot from him. We just have to be smart about how much we do play him."

Notes: The Titans brought back center Hroniss Grasu on Thursday morning with center Ben Jones in the concussion protocol. Jones missed a second straight practice Thursday. LG Rodger Saffold also is in the concussion protocol but practiced fully. CBs Malcolm Butler (hamstring) and Adoree' Jackson (foot) practiced fully after being limited Wednesday. Brown was added to the injury report Thursday after being limited by a groin injury that kept him out of most of two games before he returned last week.

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Follow Teresa M. Walker at www.twitter.com/teresamwalker