Sunday, 4:25 p.m. EDT, CBS

OPENING LINE — Patriots by 5

RECORD VS. SPREAD — 49ers 3-3; Patriots 2-3

SERIES RECORD — 49ers lead 8-5

LAST MEETING — Patriots beat 49ers 30-17 on Nov. 20, 2016 in San Francisco

LAST WEEK — 49ers beat Rams 24-16; Patriots lost to Broncos 18-12

AP PRO32 RANKING — 49ers No. 16; Patriots No. 17

49ERS OFFENSE — OVERALL (16), RUSH (11), PASS (20).




STREAKS, STATS AND NOTES — The Patriots have won four of the past five meetings. … The 49ers are 4-3 in games played in New England. … This is Kyle Shanahan's first matchup with the Patriots as a head coach. … San Francisco QB Jimmy Garoppolo faces the Patriots for first time since he was traded from New England to the 49ers in 2017. Garoppolo started two games for the Patriots as Tom Brady’s backup after being drafted in the second round in 2014. ... The 49ers gained 223 of their 268 yards receiving after the catch last week. The 9.7 yards they averaged after the catch was the second highest in the NFL this season. ... The 49ers are allowing TDs on just 46.7% of red-zone trips, the third-best rate in the league. ... San Francisco TE George Kittle is averaging 95 yards receiving per game, leading all tight ends and ranking fourth overall. ... Niners RB Raheem Mostert is out with a sprained ankle. ... Undrafted rookie RB Jamycal Hasty had nine carries for 37 yards last week. ... San Francisco allowed no sacks last week after giving up five in each of the two previous games. ... Niners WR Deebo Samuel had six catches for 66 yards and a TD last week. ... San Francisco CB Jason Verrett made his first INT since Sept. 11, 2016, last week. … New England coach Bill Belichick is 4-1 against the 49ers. … The Patriots are below .500 through five games for the first time since 2001, when Tom Brady led the team to the first of six Super Bowl titles. New England hasn’t started 2-4 since Belichick’s first season in 2000, when the Patriots went 5-11. … The Patriots are an NFL-best 65-20 in the month of October since the 2000 season. … New England has been called for a league-low 12 penalties. … The Patriots have 10 takeaways and 10 turnovers on the season. … The Patriots are 52-2 since the 2000 regular season when a player rushes for at least 100 yards. … Cam Newton enters the game with 29,912 career regular-season passing yards and needs 88 to become the 48th quarterback in league history to reach the 30,000-yard plateau. If he does, he will become the first player in NFL history to pass for 30,000 yards and rush for 5,000 yards. … Newton has five rushing TDs in 2020, tied for fourth in the league. … RB James White has 24 TD receptions in 81 career regular-season games. Brian Westbrook holds the record for the fastest running back to reach the 25-touchdown reception mark, achieving the feat in 87 regular-season games. … WR Julian Edelman had eight catches for 77 yards and a TD in the last meeting with the 49ers … CB Stephon Gilmore has an interception in two of his last three games against an NFC West opponent. … LB Chase Winovich has a sack in two of his last three games. ... Fantasy tip: Patriots CB J.C. Jackson has five pass breakups and two INTs in his past three games at home.


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