ARIZONA (2-1) at CAROLINA (1-2)

Sunday, 1 p.m. ET, Fox

OPENING LINE - Cardinals by 3 1/2

RECORD VS. SPREAD - Cardinals 1-2; Panthers 1-2

SERIES RECORD - Panthers lead series 12-5

LAST MEETING - Panthers beat Cardinals 38-20 on Sept. 22, 2019, at Arizona

LAST WEEK - Cardinals lost to Lions 26-13; Panthers beat Chargers 21-16

AP PRO32 RANKING - Cardinals No. 14; Panthers No. 20

CARDINALS OFFENSE - OVERALL (10), RUSH (7), PASS (18).

CARDINALS DEFENSE - OVERALL (7), RUSH (12), PASS (8).

PANTHERS OFFENSE - OVERALL (16), RUSH (26), PASS (7).

PANTHERS DEFENSE - OVERALL (22), RUSH (21), PASS (24).

STREAKS, STATS AND NOTES — The Panthers have won four straight games against the Cardinals and 11 of the last 14. ... Panthers coach Matt Rhule and Cardinals head coach Kliff Kingsbury met twice as college coaches with Rhule's Baylor Bears beating Kingbury's Texas Tech Red Raiders 35-24. The year before, Texas Tech defeated Baylor 38-24 ... Cardinals QB Kyle Murray has thrown five interceptions this season and has one of the league's worst QB ratings (79.7). ... Murray has 12 TDs (9 passing, 3 rushing) and four interceptions in nine career road starts. ... WR DeAndre Hopkins is averaging 118.6 yards per game since his arrival in Arizona this season in a trade with Houston. ... RB Kenyan Drake has four TDs rushing in three games. ... WR Larry Fitzgerald has 33 catches for 406 yards and a touchdown in four career games at Carolina. ... Panthers QB Teddy Bridgewater has completed 74% of his passes, third highest in the NFL. ... 2019 All-Pro RB Christian McCaffrey will miss his second straight game while on injured reserve with an ankle injury. ... RB Mike Davis had 91 yards from scrimmage and a touchdown in his starting debut with Carolina. ... Carolina's tight ends have been a nonfactor with Ian Thomas and Chris Manhertz limited to a combined six catches for 37 yards. ... LB Shaq Thompson and S Jeremy Chinn combined for 25 tackles against the Chargers. ... Panthers rookie DT Derrick Brown had three tackles for a loss last week. ... The Panthers forced four turnovers against LA. ... Carolina has allowed six TDs rushing this season. ... Panthers K Joey Slye has made 15 straight field goals dating back to last season, but has missed two extra points this year. ... Fantasy tips: Panthers WR Curtis Samuel appears to be getting more involved in the offense and could be solid flex option.

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